What are Anal Cancer Chemotherapies? List from Cancer Survivors

The below is a list that has been posted by the bloggers in this cancer community. There are 7115 cancer fighters that are members here. This is what they said, not what the doctors or nurses will tell you.

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Anal Cancer Chemotherapies

Taxol (Paclitaxel), Fluorouracil (5-FU), Mitomycin, Cisplatin (Platinol, Platinol-AQ), Adriamycin (Doxorubicin), Cyclophosphamide (Cytoxan), Avastin (Bevacizumab), Eloxatin (Oxaliplatin), Gemcitabine (Gemzar), Xeloda, Carboplatin (Paraplatin), Abraxane, Cytarabine (Ara-C)

What Anal Cancer Survivors said about their Chemotherapies.

Currently on taxol/carboplatin Prior treatment of Folfox 6 showed no sign of lung met shrinkage.
Mitomycin & Fluorouracil. Began on 7/28/08 with Mitomycin infusion done in office, 5FU infused over 96 hours by pump. Second cycle of the same began on 8/25/08. Side effects included nausea, fatigue, severe diarrhea, mouth sores, body aches, hair loss.
5 FU- Mitomycin...via port - 96 hour drip lots of side effects....transfusion at end still low white count from radiation and chemo
Starting a 5 day pump next week.
5FU: 5/18/09 to 5/21/09 and 6/15/09 to 6/18/09 Mitomycin once on 5/18 and once again on 6/15/09
June 23 to August 4. Two rounds of Mitomycin C and 5FU( I know why they call it that!!)......Fatigue, mouth sores, loss of all hair.
5-Fluorouracil and Mitomycin April 20, 2009 - April 24, 2009 May 18, 2009 - May 22, 2009 Side Effects; mouth sores, nausea, diarrhea, loss of appetite, weightloss
5FU infusion for 96 hours the first and last week of radiation. Mitomycin the first day of radiation and the first day of the last week of radiation through a PICC line
* Jul 27/09: met with Oncologist * Aug 4/09: chemo (portable pump: 5-FU) for weeks 1 and 5 until Sep 15/09; Mitomycin day 1 only of weeks 1 and 5
8-4-09 thru 8-7-09
1800 mg of capecitabine (xeloda) twice a day, 2 hour 500 ml Oxaliplatin (Eloxatine) once a week.
11-16-09
lost my ability to program...don't think like i used to..
Mitomycin and 5-FU. 75% of standard Mito dose on 1/4 due to elevated creatinine levels. Standard 5-FU dose over 5 days through chest portacath.
Mitomycin and 5-FU on continuous drip using a PICC line. 4 day drip week 1, and second 4 day drip week 5. Scheduled to begin 11/9/09. First chemo round gave me terrible mouth sores and I was extremely dehydrated, to the point of needing hospitalization. 2nd chemo round went better due to daily scheduled "hydration" sessions at oncology. No dehydration or mouth sores, but I am extremely fatigued and all my blood counts are VERY low.
Start date 11-30-2009- Mitomycin and chemo pump of 5 Fluorouracil for 4 days- week 1 & 5
No terrible side effects, the first round was heavy and I had mouth sores, but quickly learned to treat them. Little nausea, thank goodness. I was very grateful to have had the portacath rather than a picc line or the direct vain method. I watched others go through it while I was having my treatments and I felt it was easier for me to have the porta cath.
scheduled for Jan 4, 2010
First round August 3-7, second round August 31-Sept 4. Chemo effects snuck up on me. At first I felt like a brat because I felt fine and no one else at Kamp Kemo felt fine at all, and then it took me down. Nausea, constipation as a result of an anti-nausea med, diarrhea, exhaustion, loss of taste--food had texture and no flavor at all, and the texture was mostly slimy. I used salad dressing in an attempt to taste something, and ended up with slime, chicken salad--slime. And such a sore mouth, I felt like I had to fight to get a prescription for Dr. Casey's Mouth Solution, a lidocaine swish & spit, and it helped tremendously. Also low blood counts, needed a couple blood & platelet transfusions.
Started chemo Mitomycin and 5-FU on December 28, 2009 after having a Power Port placed in my chest.
Mitomycin and 5 FU beginning 1/18/10
start chemo on Jan 12 and then again on Feb 9th
weeks 1 & 5 Day 1 Mitomycin-C 10mg + 5FU 1000mg pump x 48hrs wk 1: bleeding gums, low wbc, anaemia, tiredness wk 5: nausea, low wbc, anaemia, onset of abdominal cramping, extreme fatigue hair-thinning, fatigue
01-04-10 began chemotheraphy treatment. Mytomycin infused through port at onocologist's office. Went home with an infusion pump of 5-FU (Fluorouracil) that lasted 4 1/2 days.
mitomyacin and 5fu two times over two different weekends 2009 mouth sores, weight loss, nausea,hair thinning, lightheadedness, memory loss,
12/7-10. Not too sick alot of mouth sores and counts were drastically low hospitalized 12/15 with new oncologist
Mitomycin C and 5FU infused for 96 hours (4 days) during week one and week 5 of radiation
Two rounds of chemotherapy in December '09 and January '10. Received Mytomycin at the onc office and received 5-FU using a pump on a picc line for 96 hours each round. Side effects: nausea, fatigue, loss of appetite/weight loss, some hair loss, and some vomitting during and following the second round of chemo.
5FY and cisplatin
Taking Xeloda- doing awesome on it!
Nausea, diarrhea, low white blood cells, low red blood cells, low potassium
Started Jan 4th, Mitomycin and 5FU again at 5th week
9/97-12/97, 5-FU & Mitomycin. Side effects: Loss of appetite, some mouth sores, dry mouth, swollen tongue (once), loss of taste buds.
Cisplatin and 5Fu daily for 5 days then 2 week break for 6 months low blood counts, nausea, fatigue etc. Hospitalized several times for low blood counts and infections. 12 weekly infusions of taxol, low blood counts, nausea, fatigue, neuropathy. Completed 3 of 4 A/C infusions hospitalized every time for low cell counts.
June 28 - July 4. A single 1 hour mitomycin pump followed by 4 24/7 fluorouracil pump. I like to think that I got extremely lucky with side effects. I was seriously constipated the first 4 days and put on 8 pounds in the first 48 hours. The only other side effect to this point is incredibly red blotchy skin on the face, neck and chest. I can only hope that round 2 goes as smoothly. July 27 - August 1. Intended to be the same as week 1. The mitomycin was put on hold until my platelet levels got back to normal, but we got it done. 4 bags of fluorouracil. Again, I was extremely lucky with side effects. None to speak of really and this time I didn't get the red blotchy skin on the face, neck and chest.
Mytomycin and 5-FU first weeks then 5th week
Cisplatin and 5FU, nausea and dizziness
Mitomycin given in one dose on June 28, followed by a week of infusion of 5FU. Four weeks later a second cycle of 5FU. Following the first treatment, severe mouth sores for 8 days - at the end could not swallow more than a teaspoon at a time. The second cycle had reduced mouth sores, but I did not have the Mitomycin as my blood count was too low. After the chemo ended, I developed a problem that my doctor and I identified as milk protein immune reaction (a general problem known as FPIES, and usually seen in young chidren - so at least my innards were in their second childhood!). I was hospitalized twice for rehydration, following hours of vomiting and diarrhea, after eating ice cream (it's made mostly with milk, who knew?) and a soup with light cream base (about the same as milk - who knew?). This turned me into a "food detective" when I ate away from home (what is in that sauce?). Finally, after a year, the oncologist suggested "challenges"with a fourth-teaspoon of the ice cream, followed by half-a teaspoon, etc., until I consumed the same size serving as the one that sent me to the hospital, without any reaction. At last I could stop grilling my friends about what's in the food! At this point my only issue is the chile pepper question - if something is being cooked with any kind of chile peppers I start coughing. And eating them! Out of the question.
consult 8-25
2 treatments of Mitomyicin and 2 4-day (24 hour pump) of 5-FU Started 8/31/2010
Unknown - not yet there
2/8/10 - 2/12/10: 5-FU and Mytomycin. 3/8/10 - 3/12/10: 5-FU. Nausea, loss of appetite, weight loss, lethargy, weakness, late effect hair thinning.
5-FU infusion mitomycin.. lss of appitite for a week, mouth sores.. feeling better when we took pump off.
Scheduled to begin 10/18/10, Fluorouracil and Mitomycin, 1st and 5th week
Picc line inserted Nov 17, 2010... 5fu/mitomycin started Monday Dec 6, 2010. Took a week off from radiation after second round of chemo due to unmanageable pain. Finished chemo Jan 7th, 2011 and finished radiation Feb 4, 2011.
First week and final week of radiation treatments. Chemo pump. Itchy head and chest rash within 4 days after treatment started. Minor mouth sore 1 week after. Diarrehea two weeks after. Hairloss and drop in blood counts 3 weeks after.
She has had 2 full weeks of chemo. FU5 and mitocytin. The second one they reduced the dosage as she had a violent reaction. She will finish the 2nd week of chemo on 1/21.
PICC line put in 10/25/2010 intital large dose of Mitomycin, weekly infusion of FU5, disconnected every Friday, then started back on Monday 5 1/2 weeks. By 3rd week, severe stomach pains(lasted 1 week) diarrhea, no appetite, weakness , because of blood count did not take scheduled last dose of Mitomycin
Cisplatin/5FU 4 courses may/June/ July/August 2017
has not started yet
Began 5FU and cisplatin chemo on 1/4/10 and 2/1/10 for 1 wk cycles. Side effects: nausea, vomiting, diarrhea, mouth sores, and fatigue. Hospitalized after last day of 5fu infusions for 3wks for chemo toxicity, diarrhea, severe abdominal cramping, dehydration uncontrollable fever, etc. At least I had completed menopause at age 42 and did not have to deal with the emotional side of this. Stopped HRT during treatments only.
Gi toxicity, fatigue, bone marrow suppression lasting many months hair loss, went in the hospital for a fever of 104 with low white count
Mitomycin and f5u-begin 4/12/11. . . . I was EXTREMELY tired and became EXTREMELY short-of-breath (ended up with bronchitis, but I have asthma.) One of the meds, Mytomycin, I think, can adversely affect the lungs. My thyroid got messed up so I now take meds. Nodules on lungs, on CT . . . monitoring those.
Mitromycin and 5FU via pump, 1st week and 4th week of treatment. Nausea - 4 week had to be hospitalized
To start on 4th April 2011
Starting Chemo 19 April 2011. Will be doing a 5 day Infusion 5fu for 3-4 weeks.
2/09/10 mitomycin & 5fu
Chemo pump was used only 5 days then stopped. It made my chest and upper body feel like I was going to burst.
Two 96-hour rounds of Mitomycin and 5FU on Mar 15, 2011 and Apr 11, 2011. Side effects were mouth sores, fatigue, diarrhea, loss of appetite, hair thinning.
January 2010- January 2011- Cisplatinin and 5 FU February 2011-May 2011- Oxaliplatinin and 5 FU June 2011-present - pclitaxol
5 FU - through port for 5 days June 6th and again July 5th - survived first dose with severe sore throat, mouth sores and rash. Dreading July 5th
4 days twice Fluorouracil (5-FU)and Mitomycin.
Two cycles Week one Mitomycin C & 5FU(Flouracil) Week Five 5FU
side effects; weakness, fatigue, occasional nausea.
5-FU & Mito-3 for 4 days March 2010 and April 2010
Chemo to start with radiation on Sept 26. Need a PICC. Mitomycin C and 5FU. Two weeks for five days. One week on, then three weeks off, then one week on again.
F5U 2 runs of 96 hours, Side effects included some nausea and tiredness.
Cisplatin infusion weekly for 7 weeks, 5FU 5 days a week through a picc line.
5FU and Mitomycin during 1st and 5th weeks of treatment
1st and 5th week for 4 days
Mitomycin + 5FU - twice. 1st and 5th week of radiation
1/23/2012 had IV mitomyacin then 96 hrs of 5 FU via pump. Extremely fatigued all week, not sure if it was the 5 FU or mito. Started Neupogen injections following Monday for 7 days. No nausea at all. Appetite great. Mouth sores began with a vengeance following sat and lasted 7 days. Could only swallow liquids so I mostly lived on instant breakfasts. Two weeks later my finger tips began peeling and hair loss began.
mytomycin, 5FU April and May 2010. Loss of hair, nausea, mouth sores
2 rounds (5 day hopsitalization each cisplatin and 5FU) mouth sores, some hair loss, changes in taste and smell, weight loss 6 rounds Hepatic artery infusion (oxaliplatin)avastin 3 month Jakafi (oral) unknown trial drug nano cisplatin and gemcitabine
First round 1/23/2012-1/27/2012: Some mouth tenderness, fatigue, slight nausea. Second round 2/21/2012: side effects mainly similar to the first time but not as bad. The second round had serious heartburn though.
Fluorouracil (5-FU) and Mitomycin.
2 rounds. constipation and not too much else
completed the first of chemo, mouth sores are terrible, otherwise feel ok
It seems to be the standard Mitomycin-C and 5FU in the first and fifth week of treatment. Mitomycin C dose lowered by 25% due to low WBC & platelets first time around.
Started Chemo 3/19/12 - completed 4/26/12 with mininal side effects.
March 19-23, 2012 and April 16-20, 2012: 4 days chemo (Fluorouracil and Mitomycin C)through chest port.
mytomicin at beginning and end of 6 weeks 96 hours of 5FU at beginning and end doses halved for second cycle because of bad reaction to 5FU
Taking pills(xeloda) 2 x day only on radiation days. Mitomycin IV 1st day and 28th day of radiation treatment Some nausea/Anti nausea pills help
Nausea and fatigue. Hair thinning and loss due to mytomycin.
2 rounds, 96 hours each week 1 and week 5 during radiation of 5-FU. Mytomycin-C first round only. Hairloss, nausea, vomiting, 30 pounds of weight loss. Recurrence 2013- 4 rounds of Cisplatin with 46 hours of 5-FU with each round.
Nigro protocol. Other than being tired and losing about 1/4 of my hair, the only serious side effect was mouth sores. I did have optic neuropathy for about 6 hours one week after each 5 FU.
The standard for anal cancer: two rounds of 5FU & Mitomycin. Lost about half my hair. Very bad mouth sores and oral thrush, especially in the 10 days after infusions. Became neutropenic (big drop in the type of white blood cells that are the major infection fighters) with second round of Mitomycin.
10/2011-12/2011 2 rounds of 5FU through picline., 6/2012-2/2013 Several rounds of Cisplatin
Starting Aug 27th 5FU and Mito C
Mitomycin and 5FU - 2 rounds
5/21/12 first week via port 7/2/12 2nd week via port Every third week 11/26/12 to 3/11/13, 5 hr drip 4/7/15 every 2 weeks
Xeloda Monday thru Friday. Weekends off. Also had mytomycin Iv in the beginning and end of treatment.
Mitomycin/5fu on Nov.26 for 5 days, next dose is scheduled for Dec. 24th for 5 days (Merry Christmas to me!)
Jan 7th week -1st round of chemo - severe nausea, dehydration, and mouth sores. For 2nd round 5 weeks later, started Lysine powder 1 week prior with mouthwash so no sores.
Chemo week 1 & 5 of the 6 week treatment. Mytomycin only 60% of normal dose because of high creatinine levels and 5 FU 96 hours All chemo done in patient at hospital for 5 days. Not really nausea...Zofran works wonders, BAD diareaha and painful stomach cramps...Lomotil helped with that, terrible bone pain in my arms sternun and lower back and legs from the Nuprogen to raise my white counts, headaches,one huge mouth sore on the roof of my mouth and gums were out of wack and bleeding...was given Valtrex and that did the trick
Port unplanted chemo came in a pump that I worn for 2 or 3 days. I had 2 treatments. Lost a little hair on the 1st round. The 2nd round I ended in the hospital for 8 days, just about took me out.
2 rounds, 5 days each: tiredness, metal taste in mouth, constipation
First round June 24, 2013. Vague feeling of unwell, horrible burping, relieved by Omeprazole, one and 1/2 days of sole pain, then resolved. Mouth sores began 6/29/13, peaked on 07/04/13. Second round July 22, Mitomycin reduced by half because of my WBC response the first time. Same feeling of unwell, anorexia, chemo created constipation for me, not diarrhea.
I haa a week of chemotherapy on week one (April 15-19th) and week five (May 13-May 17)) of my treatment plan. I had a pic-line put in each time for the chemo. I had both Mytomicyn and 5F-U. My first round of chemo, I had mouth sores, sore throat, and fever blisters on the mouth. My white blood count got so low that I had to have shots to boost my white blood count, and take a round of antibiotics. I also took pills to reduce getting fever blisters. My second round of chemotherapy, I was given a lower dose of the mytomicym due to the compromise of my white blood count the first time around .
Had surgery for Port placement in 01/2011. I began my first bout of chemo on 2/14/2011 along with radiation. I was in the chair for about an hour receiving the Mitomycin, and the 5-FU was portable, so it was hooked up and it was constantly dripping beginning Monday, and I would return Friday to get it taken off. I fortunately did not have too many side effects; no hair loss, not much nausea. I had a lot of fatigue, but I blame some of that on the radiation as well. Once I had my second (and final) round of chemo (which went the same way as the first), about halfway through my radiation, that's when I started to have a very difficult time and I was in a lot of pain and the effects of the radiation on my skin was much more apparent and was a lot more uncomfortable.
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