What are Anal Cancer Chemotherapies? List from Cancer Survivors

The below is a list that has been posted by the bloggers in this cancer community. There are 6899 cancer fighters that are members here. This is what they said, not what the doctors or nurses will tell you.

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Anal Cancer Chemotherapies

Taxol (Paclitaxel), Fluorouracil (5-FU), Mitomycin, Cisplatin (Platinol, Platinol-AQ), Adriamycin (Doxorubicin), Cyclophosphamide (Cytoxan), Avastin (Bevacizumab), Eloxatin (Oxaliplatin), Gemcitabine (Gemzar), Xeloda, Carboplatin (Paraplatin), Abraxane

What Anal Cancer Survivors said about their Chemotherapies.

Very fortunate to have had fairly mild chemo effects--mostly fatigue, some mouth sores etc. but not much nausea.
dehydration, some mouth sores, not bad, lost some hair. intestinal pain, tiredness, low white blood cell count and platelets, hospitalized for 11 days because I didn't want to eat and felt like I would get too weak to take care of myself. They diagnosed me with dehydration and said the treatments had caused it. Started Aug. 26 with one injection of mitomycin, and carried drip bag for four days of Flourouracil(5-FU), repeated Sept. 24th, 2013.
PICC line surgically inserted for take away 24/7 chemo, replaced weekly. skin rash on chest, drop in blood pressure, drop in red cell count requiring x3 blood tranfusions, nausea, dizziness, alternating constipation through pain meds and diarrhea from chemo/radiation combo, mouth sores, lack of appetite.
Starts 9/3/13
First Round: 9/3/2013 Received an injection (infusion?) of mitomycin, then was suited up with a mechanical pump, a bag of 5-FU, and an ugly, poorly designed fanny pack. I had to wear it for 5 days. Lots of nausea, no vomiting, very tired - which could have been caused by the anti-nausea meds that I took regularly. I basically slept my way through the first two days. I had a overall sensation of just not feeling well. After that, although I couldn't eat much, the nausea went away. On day 4, I felt really good - very slow, but good. Day 5, woke up feeling extremely weak and dreamlike. Noticed sore throat and bleeding gums (while brushing). Have developed a sore "spot" on the right side of my throat. More energy on day 6. NOTHING tasted good. :( Cramping, but no diarrhea.
1st and 4th weeks delivered by fanny pack, continuous infusion while undergoing radiation
I will begin receiving 5-FU continuous infusion Mon.-Fri. for 6wks with Mitomycin added days 1&29.
Vomiting, hair thinning but no complete loss
1st round was delayed because they could not find a vein, so I had to have a pick line surgically put in for the full time and treatment was delayed a full week as a result. I developed a very bad rash from my chest up a few days later. Overall feeling of unwell. Felt sick when I ate. I ended up in the hospital following second round of chemo. It effected my blood badly and I had to have blood and platelet transfusions and 5 days of intravenous full spectrum antibiotics. I lost about 80% of my hair, but very late compared to most people. It got especially bad for about 4 months after my last chemo.
2 rounds.. mouth sores
1st Mitomycin on Nov 18, 2013. 1st 5FU Nov 18 - Nov 22, 2013. 2nd Mitomycin on Dec 16, 2013. 2nd 5FU Dec 16 - Dec 20, 2013. Similar side effects both times: fatigue, mouth sores, gum bleeding, cramps, body pain, nausea, some vomiting, decrease white and red blood cells, some hair shedding after treatments; but much hair shedding suddenly began again two months later (not thyroid).
Day 1: March 24, 2014
7/15/13 1st round of chemo with Mitomycin and 96 hr (5 day) pump of 5-FU. Nausea, mouth sores, lack of appetite, weight loss. 8/12/13 2nd round of chemo ... same medication and side effects as 1st. Starting 7/18/14 Cisplatin, 5-FU. Every 3 weeks. Nausea, mouth sores 9/22 Carboplatin, 5-FU Every 3 weeks. Nausea, mouth changes 6/25/15 Carboplatin, Taxol every 3 weeks. Fatigue 7/15/15 Carboplatin, Taxol, Vectibix every 3 wks. Fatigue, Nausea, Dry Skin, Acne-like blemishes
Commencing Chemo 28th April
Flu type feeling... Fatigue Nausea ( took the meds every 8 hours to control) Hair thinning
Intravenous at day 1 and 30, during radiation in pill form - Mitomycin
2 weeks of chemo, the first week and last week of the 6 weeks. I had bad mouth sores both times. My hair got very thin.
First chemo started same day as radiation on 3-17-14 with a single dose of mitomycin and an infusion pump of 5-FU for 4 days. Beginning of the 5th week we repeated this process with 20% less mitomycin due to the low blood count. The first round I had few if any side effects. Felt tired and slow but when I got the pump off, I started to feel better. The second round was more difficult and my blood count fell too low, I got a low grade fever and ended up getting 2 blood transfusions and 5 shots to help build up the blood cells.
6/7/14
First round 3/17-20/14, 5-FU and Mytomycin. Nausea, fatigue, severe mouth sores (lips, mouth, tongue, throat) and white blood cell count down as low as .7. Second round postponed to 8th week due to C. Diff. infection. 1/2 dose with no severe side effects.
week 1 and week 5. Felt unwell 1st time but felt better pretty quickly. 2nd treatment really took me down. Fatigue, loss of appetite, fever- lost about 50% of my hair.
Nausea. Started chemo on August 26, 2014. Two rounds of chemo meds: one at the beginning or radiation and one at end of radiation.
April 2011 nausea and vomiting, weight loss,neutropenia,mouth sores, hair thinning April 2012 nausea, mouth sores, hair thinning
Standard protocol of 2 rounds of mitomycin & 5FU (8/13 & 9/13)
2 rounds of 96 hours each
I was completely fine up until chemo #5. All of them are 52 hours, I go home with the pump. Chemo# 5 put me down. Fatigue, mouth sores, numbness in toes, extreme sensitivity to cold, loss of appetite.
2- 5 day rounds of Mitomycin infusion followed by Flouracil pump- Severe mouth sores & tongue swelling 1st round. Had Neupogen shots x4. NeulAsta shot after 2nd round - no sores.
began Nov17 for 96 hours and again on Dec 15 for 96 hours absolute neutrophil got down to .05 on Nov 27 and spent 4 days in isolation in hospital some hair loss and fatigue
6/26/2014 began 2 rounds of 96 hour pump in a pac, thru power port , severe nausea, dehydration, malnutrition, hair loss, very low blood counts, 3 hospital stays, serious condition
No problems with chemo. Lots of itching from radiation
First week of treatment was dual with radiation. Received IV mitomycin drip for 1 hour with 5 day 24 hour power port 5fu 5th week same treatment. First treatment: nausea and severe mucositis limiting food intake. Second treatment wiped out wbc to .29 hospitalized with swollen abdomen and blocked bowel with severe abdominal pain, loss 22 lbs went down to 87lbs.
1st round week 1 December 15, 2014 nausea throughout, some hair thinning 2nd round week 5 January 12, 2015 nausea, terrible pelvic burns, hard time walking, raw, stinging while urinating and given phenazopyridine which seemed to help a bit and had to stop radiation for a week. Started back with 7 more treatments. Now 4 left to go.....
Sores in mouth, loss of appetite
I felt like my body was vibrating during the oral chemotherapy. I was very fortunate in that my side effects were minimal.
Mitomicyn, flurosil-fu-5, weeks1 and 5, minimal side effects, some hair loss and fatigue.
Mouth Sores, fatigue, nausea
1st round 23-27 March 2015 - minimal physical side effects, more pyscologial with PICC line fear and awareness of carrying chemo bottle around for a week. 2nd round 20th -24th April - felt more at ease with the bottle and had no real side effects until the end of the week, then developed terrible mouth sores around back teeth - which I didn't first time round.
Xeloda - nausea and reflux
Started March 3rd, mitomicin infusion first week, next week started Xeloda 5 days a week, last week mitomicin and zeloda. Some feet neuropathy, 1 week off of Zeloda due to very low wbc and platelets, very tired. Hard to tell what symptoms go with which treatment
96-hr infusion, week 1 and week 5, hated the clicking of the pump! About 35% hair loss on head. Total hair loss under arms and legs. Mild nausea, tired all the time, achy muscles. Ended up with a blood clot in my neck from the chemo port. Was on twice-daily injections of blood thinner for 3 months.
5 FU and Mitimycin == two rounds each. nausea, diarrhea, pain. Was in hospital for a week for low blood counts. Either blood or platelets (or both) given every day in hospital.
Mouth sores terrible lost taste for red meat. Hair thinned out
2009 - Mitfomycin, 5FU; 2011 Xeloda & Oxaliplatin; 2013 Paclitaxel & Carboplatin; 2014 Lapatinib; 2015 Xeloda (twice with radiation)
mitomycin on 6/29/2015, 5day infusion of 5-FU 6/29 - 7-4 Side effects "metal mouth" loss of appetite, fatigue
4 days 96 hours
Mitomycin on Day 1 and Day 29 5-FU Days 1-4 and 29-32 Dry mouth, constipation, thinning hair at week 4. <<<<<<After reading this I have to say "chemo brain" because I don't recall writing that!!
Fatigue, nausea, mouth sores, hair loss. Developed an abdominal infection after the first round and was hospitalized for 10 days.
Mitomycin, 5FU. Mucosytis, oral thrush
1st round 9/28/15: Mitomycin infusion; 5FU drip for 4 days. Stupidly stopped taking anti-nausea med Zofran for a day because it was making me constipated and proceeded to get sick throughout the night. Started taking Compazine instead. Developed thrush/mouth sores once finished with chemo - they lasted a week. Next round of chemo coming up 10/19/15.
Overall unwell feeling. I had chest tightness and pain, might have been from anxiety. I was lucky with minimal hair loss and had only light nausea. I took my nausea and pain medication as prescribed, not when I needed it. Once nausea sets in, it's very hard to get rid of it. While I did not like taking opioid pain medication, pain is like the nausea, once it sets in, it's hard to overcome. About two weeks after radiation concluded, the Dr. and I ''weaned'' me off the pain medication with over the counter pain meds. The last week of Chemo was the worst, in hospital for a week as I spiked a fever, got some heavy duty antibiotics.
XELODA 500mgs x2 twice a day for two weeks during radiation. Recommenced 14.10.15 to stop on 28.10.15...Having this treatment as insertion of PICC line failed and ceases during radiation due to platelets dropping to 108.
Cisplatin and Xeloda front 20/08/14 through to 11/11/14 Sickness at the start of cycles 1 and 2. Swelling in my legs on the start of cycle 2. Dose was reduced for cycles 3 and 4 . I did not get along with the anti sickness tablets, I tried several different ones. EMEND was usefully but I stopped taking others and found ginger to be most helpful. I seemed to experience a little of all side effects. Ulcers, hand and foot syndrome, diarrhoea sickness and constipation but they didn't last long. Oh and my head hair thinned but I did keep enough.
Cisplatin and 5fu 9/23/15 pump 96 hours/week 1, repeated 4th week 10/21/15 mouth sores, partial hair loss, oral thrush, dehydration, loss of potassium.
2weeks of Chemo. Starting the first week of radiation and the last week. Mouth sores low blood pressure. Second round of chemo mouth sores. Hospitalized due to UTI for a week. Spent a month in the hospital. It was hard to recover
Mitomycin & 5FU started on 1/18 ended on 1/22. Next chemo to start on 2/15. Side effects were constipation, fatigue and low appetite and aversion to smells.
inpatient 5 days 23 hrs a day twice
june 15-August 6, 2015
Dates 1/31/15, 2/19/15 Type, F5
2 rounds via port, less than 96 hrs round 1 due to New Year's Eve infusion clinic closing, 96 hrs round 2, Low WBC, fatigue, port infection,
Mytomycin and 5-FU weeks 1 and 5. Facial outbreak from 5-FU, sensitivity to spicy anything. By end of 1st week my mint toothpaste was too much.
Nausea, loss of appetite, chemo brain.
FU and mitomycin. Extreme exaustion, WBC dropped to 0.9. Hospitalized.
2 weeks started 21 July 2016- 25 July 2016
Mitomycin and Fluorouracil (5- FU) for four day at beginning and four days at end. Start date 8/22/2016.
Did well with the first round of chemo. Only side effects were loss of appetite and mild nausea. Did well again with my second round of chemo. Did not lose my hair!
5fu and Mitomycin Feb-Mar 2014
6/20/11 5 days; 7/18/11 5 days fatigue, nausea, parageusia, mouth sores, vomiting, hair loss, dry skin, brittle dark nails, low blood pressure, urine & stool incontinence, 2 blood transfusions, vitamin deficiencies
Luckily just 2 rounds of Chemo in 2000. Only lost hair from the waist down. Which would be awesome if I was pursing a career as a Drag Queen
Capacitabine (Xeloda) 5 x week, 2 x day in tablet form Nausea WBC low, needed to stop chemo treatment for 10 days Hb low, needed 2 x blood transfusions
2 rounds of chemo, lost a lot of hair but not all, delayed healing of burns, caused yeast infection.
First round...mouth sores, nausea, weight loss, chemo rash on face and on upper torso, hair loss (about 80%).
Will start 1/27/17
Started chemotherapy on 2/21/17 and ended on 3/29/17
May-June, 2015; 5-FU and Mitomycin
03/27/17- Mitomycin IV push; 5-FU began 96 hour infusion
peripheral neuropathy
None yet
May 2015, 6 weeks. Hair loss, weight loss, nausea
07/01/2016 1st chemo w/Cisplatin + FU5 (4 day tube) 07/29/2016 2nd chemo 80% w/Cisplatin w/FU5 (4 day tube) 08/03/2016 got infusion of fluids and magnesium
Nausea
None Was tod too weak to get it
pills, started on the same day
not yet determined
Taste buds, no desire to eat and big weight loss.
Haven't started yet
Chemo first and fifth week. Mouth sores, nausea, and no appetite.
Some nausea, kept most of my hair.
Wore chemo injector for two weeks in November of 2012 with 3 weeks between each week while receiving radiation. Hospitalized 2 days for extreme chest pain due to chemo.
2 IV chemo treatments, on day one, then 2nd delayed due to dehydration, also 6 pills/day for 30 days, same timing as radiation, very tired, no appetite, lost 15 pounds
5 FU and mitomycin
5FU and mitomycin. Lost all my hair, severe mouth sores, fever from extremely low blood counts, tired, nausea, two hospital stays for a week each time.
Week 1 Nov 6 thru Nov 10. Second round cones Nov 27 thru Dec 1.So far mouth sores.
Fatigue, hair thinning,
Chemo started 3/14 - 3/19. Nausea lingered under surface the whole time. If I missed the anti nausea pill by 1/2 hour it’d take all day to catch back up. Mouth sores started on day 4. I caught a cold that stared on day 2 with a sore throat, full sinuses, lungs etc. the mouth sores progressed quickly and caused the sore throat to become excruciating. I’m still struggling to eat and get enough fluids. I was given iv fluids 2 days after the pump was taken off. And I’m currently trying to not have to go there again. Mouth sores finally abated after 2+ weeks. Unfortunately food still sounds awful, nothing tastes good and I start feeling bad after every time I eat. The blister in my bum apparently is from the chemo not the radiation. Great news is my doc is cutting the dose for 2nd round by 25% because I’m a slow metabolizer. Great. I hope it helps!with round 2 (which starts in 10 days -ugh) I’ve also started experiencing hypersensitivity on my upper left leg, and occasionally on my feet and hands. Started taking B6 to help. Hair started falling out 2 weeks after chemo- getting it cut short end of week 3.
Airless, nails less, going crazy from Decadron - steroids DO NOT agree with me
5-FU Two rounds done in the hospital W-M 24 IV drip into my lovely port I named Randy. Blistering Lips - Acupuncture helped that tremendously. I did it once a week everyday of treatment and for about a month and half after. I still go now for tuneups. Blackmouth/teeth/tongue - baking soda on my toothbrush got rid of that Diarrhea - a towel to scream into when it was bad; childs pose when I was finished; I will finish this I have lots of things I did.......
nausea (finally controlled).
5-21-18 thru 7-18-18. started with xeloda pills but could not keep them down. Switched to 5fU pump 24/7 for 8 weeks. Mostly tired, diarrhea during radiation but got better after. good days, bad days.
AM NOT USING THE 5-FU....INSTEAD ITS CAPECITABINE 500MG
Pill Chemo - Xeloda 500 mg. 4 pills AM 3 in PM. Zofran for Nausea. 2 IV push of Mitomycin during the 1st & last radiation treatments. MItomycin IV side effects - Metallic taste in everything lasted 24 hours Xelolda - Annoying tingling in hands, legs & feet which went away week 1. Nausea waves Stomach pains in lower abdomen Constipation
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