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What Fluorouracil (5-FU) Cancer Survivors said about their Chemotherapies.
Nigro protocol. Other than being tired and losing about 1/4 of my hair, the only serious side effect was mouth sores. I did have optic neuropathy for about 6 hours one week after each 5 FU.
Fluorouracil (5-fu), Oxaliplatin, Avastin, leucovorin. 1/15-3/2? Side effects - Extreme fatigue, nausea, cold sensitivity, neuropathy
Chemo doable. Nausea, constipation (turned out my gall bladder wasnt funtioning but had to wait for surgery until long after completed therapy.)Dehydrated one time (walked for hour outdoors as it was a lovely day) so badly home nurse came to house to hook me up to fluids and it worked immediately. Radiation was more difficult in that I knew, due to light skin, that I would be much more burned. I was surprised when the treatment was over that I continued to be radiated though I wasn't receiving radiation but felt I was receiving it daily for approximately two more weeks.
Alt Folfiri/Folfox 2010/Feb through 2010/June Folfiri/Erbitux started 2011/March Changed to Folfox/Avastin 2011/Oct Clinical trials 2012/Sept
The standard for anal cancer: two rounds of 5FU & Mitomycin. Lost about half my hair. Very bad mouth sores and oral thrush, especially in the 10 days after infusions. Became neutropenic (big drop in the type of white blood cells that are the major infection fighters) with second round of Mitomycin.
Neuropathy in toes arms diarreha constitpation pain when going. I have fissures now because of not being able to go which is causing bleeding and immense pain even hours after. Pain in jaw when I first eat. heart palpitations. No more mouth sores or fevers since I have been taking vitamins b and magnesium with zinc. Numbness in both hands and feet and cramping
10/2011-12/2011 2 rounds of 5FU through picline., 6/2012-2/2013 Several rounds of Cisplatin
3 doses of Cisplatin.
Starting Aug 27th 5FU and Mito C
Mitomycin and 5FU - 2 rounds
First treatment on 8-16-12 of FOLFOX Avastin begins 8-30 with second treatment Side effects: mouth soreness, sensitivity to cold
Folfox6 November 13, 2012. 12 treatment cycles over 6 months, end date April 18, 2013. Oxaliplatin-allergic reaction, tongue numbness, profuse sweating, numbness in hands. Benadryl for two days. Immediate neuropathy in hands and feet, sensitivity to cold, very weak, chest pressure, numbness and tingling in limbs. 5FU- nausea' headache, diarrhea, itchy skin, no appetite, vision problems, dizziness
1st session, September 20th. Once a week for 3 weeks then 1 week off. October 25th, white blood cell count was down for the 1st time, so they skipped chemo for that week. November 1, 2012, white blood cell count back up so they did chemo. December 2012 started 5 FU, Oxaliplatin and Leucovorin every 3 weeks to target the abdominal lining tumors that are continuing to grow. April 19, 2013, CT shows the chemo isn't working on the abdominal lining tumors, and they have given him the best chemo treatments they have, nothing more they can do. But will reduce the chemo he has been on to reduce painful sores in his mouth and side effects that were getting worse with each treatment, I think to keep the liver and pancreas tumors at bay and hopefully still give him pain relief.
5/21/12 first week via port 7/2/12 2nd week via port Every third week 11/26/12 to 3/11/13, 5 hr drip
5FU,Oxaliplatin and leucovorin
Mitomycin/5fu on Nov.26 for 5 days, next dose is scheduled for Dec. 24th for 5 days (Merry Christmas to me!)
Jan 7th week -1st round of chemo - severe nausea, dehydration, and mouth sores. For 2nd round 5 weeks later, started Lysine powder 1 week prior with mouthwash so no sores.
Jan 21- vomit, headaches, fatigue, lack of sleep, sore throat, cold sores, dry mouth, weak, pain, dry skin, headaches
June 2012-October 2012; Reported Lethargy, nausea, changes in taste, neuropathy in fingers, weight loss.
Chemo week 1 & 5 of the 6 week treatment. Mytomycin only 60% of normal dose because of high creatinine levels and 5 FU 96 hours All chemo done in patient at hospital for 5 days. Not really nausea...Zofran works wonders, BAD diareaha and painful stomach cramps...Lomotil helped with that, terrible bone pain in my arms sternun and lower back and legs from the Nuprogen to raise my white counts, headaches,one huge mouth sore on the roof of my mouth and gums were out of wack and bleeding...was given Valtrex and that did the trick
March 22(3 types of chemo) i feel it lessened his quality of life, but for my dad he needed to fight back!!!
chemo from 2/98 through 9/98
cisplatine caused hearing damage, taxotere caused skin and nail damage and herceptin made my hands tingle. Xeloda wiped me out, and all of the above caused hair loss.
Port unplanted chemo came in a pump that I worn for 2 or 3 days. I had 2 treatments. Lost a little hair on the 1st round. The 2nd round I ended in the hospital for 8 days, just about took me out.
5FU & Oxaliplatin
2 rounds, 5 days each: tiredness, metal taste in mouth, constipation
First round June 24, 2013. Vague feeling of unwell, horrible burping, relieved by Omeprazole, one and 1/2 days of sole pain, then resolved. Mouth sores began 6/29/13, peaked on 07/04/13. Second round July 22, Mitomycin reduced by half because of my WBC response the first time. Same feeling of unwell, anorexia, chemo created constipation for me, not diarrhea.
I haa a week of chemotherapy on week one (April 15-19th) and week five (May 13-May 17)) of my treatment plan. I had a pic-line put in each time for the chemo. I had both Mytomicyn and 5F-U. My first round of chemo, I had mouth sores, sore throat, and fever blisters on the mouth. My white blood count got so low that I had to have shots to boost my white blood count, and take a round of antibiotics. I also took pills to reduce getting fever blisters. My second round of chemotherapy, I was given a lower dose of the mytomicym due to the compromise of my white blood count the first time around .
Had surgery for Port placement in 01/2011. I began my first bout of chemo on 2/14/2011 along with radiation. I was in the chair for about an hour receiving the Mitomycin, and the 5-FU was portable, so it was hooked up and it was constantly dripping beginning Monday, and I would return Friday to get it taken off. I fortunately did not have too many side effects; no hair loss, not much nausea. I had a lot of fatigue, but I blame some of that on the radiation as well. Once I had my second (and final) round of chemo (which went the same way as the first), about halfway through my radiation, that's when I started to have a very difficult time and I was in a lot of pain and the effects of the radiation on my skin was much more apparent and was a lot more uncomfortable.
Very fortunate to have had fairly mild chemo effects--mostly fatigue, some mouth sores etc. but not much nausea.
dehydration, some mouth sores, not bad, lost some hair, ruined my hairstyle, intestinal pain, tiredness, low white blood cell count and platelets, hospitalized for 11 days
PICC line surgically inserted for take away 24/7 chemo, replaced weekly. skin rash on chest, drop in blood pressure, drop in red cell count requiring x3 blood tranfusions, nausea, dizziness, alternating constipation through pain meds and diarrhea from chemo/radiation combo, mouth sores, lack of appetite.
Feb. 1-July 22, 2013, 11 rounds. Oxyaliplatin, 5FU and Leucovorin. Side effects - fatigue, stomach issues, sensitive to cold (whether eating, drinking, touching or being in the cold), neuropathy in both hands and feet (very debilitating, numbness - hard time walking and in the hands, fingertips especially feel like they are burned.
First Round: 9/3/2013 Received an injection (infusion?) of mitomycin, then was suited up with a mechanical pump, a bag of 5-FU, and an ugly, poorly designed fanny pack. I had to wear it for 5 days. Lots of nausea, no vomiting, very tired - which could have been caused by the anti-nausea meds that I took regularly. I basically slept my way through the first two days. I had a overall sensation of just not feeling well. After that, although I couldn't eat much, the nausea went away. On day 4, I felt really good - very slow, but good. Day 5, woke up feeling extremely weak and dreamlike. Noticed sore throat and bleeding gums (while brushing). Have developed a sore "spot" on the right side of my throat. More energy on day 6. NOTHING tasted good. :( Cramping, but no diarrhea.
Chemo was 1 day a week for 5 weeks and I went after I had my radiation treatment. They made me very tired and weak feeling. Some days I just had to go home and go to bed. Was only sick a couple of times but kept diarrhea the whole time I was having the chemo treatments, going to the bathroom some days as many as 11-12 times.
begun 26 September 2013
1st and 4th weeks delivered by fanny pack, continuous infusion while undergoing radiation
Folfox mix of chemotherapy -nausea, vomiting, diahhrea , nil taste I food, shaking, mouth ulcers, dry skin
May 2010-July 2010: 24 hour, continuous 5FU infusion, Mondays-Fridays November 2010-January 2011 :Folfox December 2011-April 2012
I've been on some sort of chemotherapy for 21 months now. I've been lucky that the side effects haven't been too horrible. I would get a little sick here and there but everything was mostly tolerable and I've been able to function quite well.
I will begin receiving 5-FU continuous infusion Mon.-Fri. for 6wks with Mitomycin added days 1&29.
Folfirinox Jan 2013 - Feb 2013, switched to Abraxane and Gemcitabine March 2013-current
FOLFOX started 2/11/2012 and ended on 7/18/12. The oxaliplatin in the FOLFOX caused peripheral neuropathy.
Fluorouracil - 2 doses, 5 weeks apart Mitomycin - 2 rounds of 96 hours each, also 5 weeks apart The usual unpleasant side effects.
Vomiting, hair thinning but no complete loss
1st round was delayed because they could not find a vein, so I had to have a pick line surgically put in for the full time and treatment was delayed a full week as a result. I developed a very bad rash from my chest up a few days later. Overall feeling of unwell. Felt sick when I ate. I ended up in the hospital following second round of chemo. It effected my blood badly and I had to have blood and platelet transfusions and 5 days of intravenous full spectrum antibiotics. I lost about 80% of my hair, but very late compared to most people. It got especially bad for about 4 months after my last chemo. Low hemoglobin and very anemic as a result still.
14 days Xeloda, IV infusion consisting of Oxaliplatin, 5FU, Avastin, Palonosetron HCL, Dexamethasone, Leuvovorin, Potassium.
currently undergoing treatments
2 rounds.. mouth sores
1st Mitomycin on Nov 18, 2013. 1st 5FU Nov 18 - Nov 22, 2013. 2nd Mitomycin on Dec 16, 2013. 2nd 5FU Dec 16 - Dec 20, 2013. Similar side effects both times: fatigue, mouth sores, gum bleeding, cramps, body pain, nausea, some vomiting, decrease white and red blood cells, some hair shedding after treatments, but much hair shedding suddenly began again two months later (not thyroid).
Began with Xeloda in pill form that was simultaneous with my Radiation. 6 weeks Mon-Fri. Didn't have any problems with this drug whatsoever. March 2014 began Oxaliplatin and 5FU for the next 6 months. I where a pump for 48 hours of continuous infusion every other week. I was told to be cautious of cold weather and cold drinks or any other type of cold items. So drinking everything at room temp is pretty boring but I did find out what happens if you do try to tempt fate and drink a cold substance----it felt like I was swallowing shards of glass down the back of my throat. YIKES. So far, I have only noticed a bit of nausea during the week of treatment and fatigue, but I know it is early and these symptoms will undoubtedly worsen as time goes on. Not looking forward to this. Really have dreaded the whole chemo thing.
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